AEON Biopharma: Better than “Botox”?
By now, Botox has become a common treatment for migraine. But AEON Biopharma wants to create a similar but better treatment.
Botox is a brand name for injections made from botulinum toxin A, specifically onabotulinumtoxinA. Given by injection, it has been helpful as a migraine preventative.
In spite of calls for standardization, the fact is that we still have a lot to learn about how to best use botulinum for migraine. How many injections is best? Where should the injections be? How often? Is there a difference for different types of migraine?
Another type of botulinum toxin A is prabotulinumtoxinA (PRA). Like onabotulinumtoxinA (ONA), PRA is used to fight wrinkles. Different types of botulinum come from different sources and processing.
AEON wants to use their own special version of PRA to help prevent migraine. And they’re hoping that they can do it with fewer injections than the typical Botox treatment.
This new treatment is currently known as ABP-450. ABP-450 is entering into phase 2 trials in Australia, Canada, and the USA, so you can check out more information here if you’re interested in being involved. Both episodic and chronic migraine patients are invited.
ABP-450 is also being studied as a treatment for cervical dystonia, a painful condition involving neck spasms.
For more information, check out AEON’s official press release here: AEON Biopharma Initiates Enrollment in Phase 2 Trial of ABP-450 for the Preventive Treatment of Migraine