Comments on: New Migraine Drug Telcagepant – Not Dead Yet http://headacheandmigrainenews.com/new-migraine-drug-telcagepant-not-dead-yet/ Thoughts and information about the latest news in the world of migraine, cluster headache and other headache treatment around the world. Thu, 18 Mar 2010 15:20:09 +0000 http://wordpress.org/?v=2.9.2 hourly 1 By: Candace http://headacheandmigrainenews.com/new-migraine-drug-telcagepant-not-dead-yet/comment-page-1/#comment-42438 Candace Tue, 29 Dec 2009 00:24:28 +0000 http://headacheandmigrainenews.com/?p=1195#comment-42438 I posted above on 10-22-09 and believe I have found my answer in a book called "The Magnesium Factor". Dr. Mildred Seelig says that if magnesium status is very low and Vitamin D intake is very high, calcium absorption can be high enough to make magnesium deficiency worse. She also said low magnesium can lead to Vitamin D resistance, which in my case seemed to be true. I was taking 8000 IU of D3 a day and only got up to 52 ng/ml on my Vitamin D blood test. So I started taking 400 mg. of Ultra Mag (Vitacost) at night, separate from the Vitamin D and calcium in the morning. After a couple of weeks, my headaches stopped completely. I haven't had head pain for a month now. I am also no longer waking up with palpitations and feeling like I don't have enough oxygen. I thought for a while that I had sleep apnea. I had tried magnesium oxide combined with calcium earlier in my life, but it didn't work. This magnesium chelate is wonderful. I'm sure it won't work for everyone, but I am so happy that I happened upon this website and decided to give magnesium another try. I posted above on 10-22-09 and believe I have found my answer in a book called “The Magnesium Factor”. Dr. Mildred Seelig says that if magnesium status is very low and Vitamin D intake is very high, calcium absorption can be high enough to make magnesium deficiency worse. She also said low magnesium can lead to Vitamin D resistance, which in my case seemed to be true. I was taking 8000 IU of D3 a day and only got up to 52 ng/ml on my Vitamin D blood test.

So I started taking 400 mg. of Ultra Mag (Vitacost) at night, separate from the Vitamin D and calcium in the morning. After a couple of weeks, my headaches stopped completely. I haven’t had head pain for a month now. I am also no longer waking up with palpitations and feeling like I don’t have enough oxygen. I thought for a while that I had sleep apnea. I had tried magnesium oxide combined with calcium earlier in my life, but it didn’t work. This magnesium chelate is wonderful. I’m sure it won’t work for everyone, but I am so happy that I happened upon this website and decided to give magnesium another try.

]]> By: Candace http://headacheandmigrainenews.com/new-migraine-drug-telcagepant-not-dead-yet/comment-page-1/#comment-33248 Candace Fri, 23 Oct 2009 02:51:11 +0000 http://headacheandmigrainenews.com/?p=1195#comment-33248 Because of all the news about how high Vitamin D levels are so good at preventing cancer, I doubled my dose of Vitamin D3. I am definitely not at too high a blood level, but my migraines have increased to almost daily from twice a week. Since this new migraine preventative drug is a "calcitonin gene related peptide receptor antagonist", I am wondering if my increased D3 levels may have led to the increased migraines. All I know is that Vitamin D3 has something to do with calcitonin, but I don't know how this might be related to increased migraines. I would hate to have to quit the D3, but obviously would do it if necessary to stop the daily pain. Because of all the news about how high Vitamin D levels are so good at preventing cancer, I doubled my dose of Vitamin D3. I am definitely not at too high a blood level, but my migraines have increased to almost daily from twice a week. Since this new migraine preventative drug is a “calcitonin gene related peptide receptor antagonist”, I am wondering if my increased D3 levels may have led to the increased migraines. All I know is that Vitamin D3 has something to do with calcitonin, but I don’t know how this might be related to increased migraines. I would hate to have to quit the D3, but obviously would do it if necessary to stop the daily pain.

]]> By: James http://headacheandmigrainenews.com/new-migraine-drug-telcagepant-not-dead-yet/comment-page-1/#comment-32684 James Thu, 15 Oct 2009 00:51:20 +0000 http://headacheandmigrainenews.com/?p=1195#comment-32684 Good to hear from you, Ann! Maybe if this line of research is continued, there will be more hope that the preventative line will be reconsidered as well; if not with telcagepant, maybe with other related medications. Good to hear from you, Ann! Maybe if this line of research is continued, there will be more hope that the preventative line will be reconsidered as well; if not with telcagepant, maybe with other related medications.

]]> By: Ann http://headacheandmigrainenews.com/new-migraine-drug-telcagepant-not-dead-yet/comment-page-1/#comment-32513 Ann Tue, 13 Oct 2009 19:16:49 +0000 http://headacheandmigrainenews.com/?p=1195#comment-32513 This is really great news! I was in one of the preventive treatment trials with MK-3207 before it was discontinued because of the liver problems in some participants. For me, it worked wonderfully! I had fewer migraines and almost no milder headaches, and when I did have a migraine, it responded much better to my normal Triptan course than usual. I'm so happy to hear that there's a possibility that a similar drug will be introduced to the market someday! This is really great news! I was in one of the preventive treatment trials with MK-3207 before it was discontinued because of the liver problems in some participants. For me, it worked wonderfully! I had fewer migraines and almost no milder headaches, and when I did have a migraine, it responded much better to my normal Triptan course than usual. I’m so happy to hear that there’s a possibility that a similar drug will be introduced to the market someday!

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