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12 Comments

  1. MaxJerz
    30 October 2008 @ 10:01 pm

    My herbalist just started me on Primadophilus Optima for my IBS. She recommended that particular brand for exactly the reasons you cite.

    I did also want to say that iHerb.com sells it, and they ship it in a refrigerated carton. It retails there for about half-price.

    I’m hoping that the probiotic helps. My herbalist did also mention that this specific brand has been clinically studied, and shows a lot of benefit over other brands.

    Be well,
    MJ

    Reply

  2. James
    31 October 2008 @ 7:47 am

    Glad to hear your herbalist agrees with me (if she’s a good herbalist, that is!)!

    Yes, the refrigerated carton is a nice feature. The other places I mentioned above are a little cheaper than iHerb, but shipping prices vary. Also, they only ship in the refrigerated carton within the USA, I believe, so elsewhere you lose that benefit.

    Here’s Primadophilus Optima at iHerb. If you’re a first time customer you can save $5 with this coupon: RIL032

    Then you can get more credits by referring others. 🙂

    If you’re ordering regularly, check all three of the places we mentioned, all of which are reputable vendors, and check which is cheapest where you are.

    Reply

  3. Mary Kay
    1 November 2008 @ 11:50 am

    One theory about the connection between IBS, migraine and anxiety lies in the receptor sites involved in each. The are called 5HT receptors..most are in the gut (IBS!) and many types are in the brain and known to be involved in migraine and anxiety. Although the exact link hasn’t been made yet, it would make sense that when one group fires off..the others might.

    This could explain why in the middle of a migraine, many people have more anxiety and even diarrhea.

    Reply

    • Seth Kaplan
      24 April 2011 @ 6:16 am

      Actually, some neurologists have understood the connection between receptor sites for decades! Here is how it was described to me: (1) serotonin leaves the brain for one of the many reasons that starts the migraine process; (2) serotonin likes to hide on gut receptor sites and does so; (3) after about :30 minutes, the receptor sites release dopamine, which goes to the brain, initiating the migraine.
      There is a way to stop the serotonin from hiding in the receptor sites. It’s an old prescription antihistamine called periactin, or cyproheptadine. A little 10Mg pill, it attaches to the gut receptors and blocks the serotonin from hiding there. When they can’t hide, they return to the brain (a nice rush!). When taken within the :30-minute window, periactin averts the migraine, which is a nice ending to this story. The only proviso is that one cannot take periactin if one also takes an SSRI.
      Hope this helps!

      Reply

  4. James
    6 November 2008 @ 7:46 am

    Thanks for mentioning that, Mary Kay. I believe that is and important connection, which is why I keep coming back to talking about the gut.

    Reply

  5. Donna | Eat Healthier
    19 November 2008 @ 4:38 pm

    Interesting article. There are so many things in our modern diets and lifestyles that can kill these beneficial gut bacteria that it’s important to make sure we re-establish them. Our intestinal flora is not just ‘nice to have’ it’s essential, and not surprising that lack of healthy gut bacteria is a cause or contributor to IBS. The reason I’ve not used probiotics yet is exactly because I know that not all are going to be created equal and I don’t want to waste my money on something that’s not going to do the job. Thanks for your recommendation.

    Reply

  6. James
    24 November 2008 @ 6:36 am

    You’re welcome. 🙂

    Reply

  7. Soraya
    8 December 2009 @ 6:31 am

    The UK company OptiBac Probiotics offers a range of probiotics which are tailored to specific needs. ‘For daily wellbeing’ is multi-strain, shelf stable, with added prebiotics (food for the probiotics to grow) and gives 5 billion micro organisms per daily dose, guaranteed right up until the end of the expiry date. Worth checking out!

    Reply

  8. James
    10 December 2009 @ 10:20 am

    I would love to see some independent research on OptiBac Probiotics. I have chosen to mention the brand I have mentioned after reading independent research on, for example, how much of the active ingredients actually survive long enough. Many companies make great claims, but it’s hard to know which is the best until you see some studies done.

    Reply

  9. Soraya
    18 December 2009 @ 8:08 am

    Sincerely appreciated James.

    Clinical trials on the products are listed at the bottom of each product page on the website, or also on the Evidence and Testimonials section. – http://www.optibacprobiotics.co.uk/optibac-probiotics-evidence-testimonials.html
    Alternativley, you can read up on survival of stomach acidity etc with the Institut Rosell, who manufacture probiotic strains for OptiBac.

    Reply

  10. Michael
    22 January 2010 @ 6:38 pm

    great post–
    I have had migraines for years, and knew they were linked to my diet, specifically dairy. Then in 2007, I got food poisoning and developed IBS as a result. The curious thing was that my migraines went away with the arrival of the IBS. Every time I ate dairy, I would then get diarrhea and all sorts of pains. Eventually I read Dr. Pimental’s (sp) book “a new IBS solution” regarding IBS and bacteria, and I altered my diet and took culturelle (/lactaid when eating dairy), and my IBS pretty much went away, but my headaches came back! One day I read about the tyramine/histamine production by bacteria involved in food production (cheese, sausage, etc). and it was an epiphany for me.
    I still am trying to get the right situation going on in my gut, but I suffer from fewer migraines than in the past and have very infrequent IBS symptoms, unless I really go nuts on the cheese!

    Michael

    Reply

  11. Mark
    17 August 2010 @ 1:38 pm

    It’s taken me years to realize that not only histamine, but tyramine, are implicated in inducing manias in me(I have rapid cycling bipolar). Along with fermented foods, including yogurt & kefir, tomatoes, chocolate, avacados, bananas, almonds, pickled fish & all alcohol contain tyramine.

    I’ve used probiotics in the past but I’ve gradually become sensitive to so many foods that I’m going to flood my gut with both liquid and capsulated probiotics since my doctor doesn’t know what to do with me. So much for having health insurance, lol.

    Mark

    Reply

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