Grape Seed Extract – Next for Migraine?

Could grape seed extract be the next big supplement used to combat migraine?  Researchers at the Missouri State University think it may be.

Grape Seed Extract

Grape seed extract has been researched heavily in the last few months.  It shows a lot of promise in areas such as fighting hyperglycemia and its antioxidant properties.

This was another trial on rats.  Some were fed regular water, others water with grape seed extract.  Otherwise, their diet was normal.

The results showed that the grape seed extract helped to fight inflammation, and suppressed reaction which seem to stimulate "central sensitization" – a key part of the migraine chain-reaction.

The researchers felt that the evidence was strong for the trial of grape seed extract (GSE) in migraine patients.  They write:

Based on our findings, we predict that inclusion of GSE as a dietary supplement would be beneficial as a natural therapeutic option for chronic migraine as well as other chronic pain conditions involving the head and face.

The report was given at the 52nd Annual Meeting of the American Headache Society last month.

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5 comments… add one
  • Emily Jul 17, 2010

    A research report from where I live! Have taken classes there – small world. Thanks James!

  • Hank Billings Sep 9, 2010

    Polyphenolics’ MegaNatural-BP Grape Seed Extracts have been in the spotlight recently. They just received an Award from Frost & Sullivan, a leading analyst and market research firm. See link here:

  • Deirdre Slocum Apr 16, 2012

    I had severe, frequent migraines that nothing helped, until I tried Grape Seed Extract. I have been headache free for 4 years!

  • caroline Dec 11, 2015

    I’ve never had a migraine BUT haven’t had a headache in about 20 yrs. I’ve been taking Grape Seed Extract for 2 decades and my allergies/sinus issues are history.

    Makes sense to me WHY NOT get on Grape Seed Extract for all headaches/circulation help.

  • John Bedson Mar 7, 2017

    Grape seed extract inhibits the action of CGRP. The expensive new migraine CGRP inhibiter drugs reduce the action of CGRP.

    Hmmmmm. There might be a connection!

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