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9 Comments

  1. Ellie Marie Moore
    6 June 2013 @ 10:57 pm

    This is very interesting, thank you.

    Reply

  2. Dee Ball
    7 June 2013 @ 12:21 am

    Interesting! ESP after a week of hay fever and migraine symptoms!

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  3. Kirstin Roma Lavender
    7 June 2013 @ 3:02 am

    Very much so! I developed migraines (a 9 week lon gone so far) have been checked out for anything scary and all ok but I started to get bad hives with it too so that conection as possibility too. Many thanks 🙂

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  4. Sayed Tehmiid Abbas
    7 June 2013 @ 6:18 am

    anti histamine cetrazine also induces migraine in my particular case.

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  5. chris
    8 June 2013 @ 3:18 am

    Had the problem related to this but only when I had a sneezing fit, when I controlled the sneezing I didn’t get a migraine. Sneezing makes you use the muscles in the face and neck very suddenly.

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  6. kim
    16 April 2018 @ 9:21 am

    This may explain why some people on migraine groups that I follow talk about getting relief from taking benadryl for a migraine. Any thoughts on this ?

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  7. Mary Ann Young
    19 April 2018 @ 1:41 pm

    In response to Kim’s note on 4-16-2018: Your comment is interesting because I found Benadryl effective once last week for a quickly exacerbating migraine in the morning. Our pollen and mold counts have been high for quite some time here in Austin, TX. Customarily, I have been taking loratidine and pseudoephedrine (12-hr) as soon as I awaken for the day, and often two Excedrin tabs for the rapid onset headache. I often have to repeat the Excedrin towards early evening, but this usually takes care of the migraines within a half hour during my migraine cycles every 6-8 weeks.

    However, on this particular day, a pounding migraine awoke me about 3 am, and I took two Excedrin then with prompt relief. Then, around 9 am, the migraine was returning and I had nothing safe to take for it. I decided to take 25 mg of Benadryl for the first time, thinking that the environmental allergens might be blowing up the symptoms. Surprisingly, it seemed to work.

    I have never heard of Benadryl being helpful during a migraine, so your comment has caused me to explore this a bit.

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  8. Tracy
    14 October 2018 @ 10:33 am

    I just happened to stumble across this and very interesting connection here. I am 35 and when I was 29 I had an ongoing migraine, never had one before. They didnt stop for minths on end. I had every test imaginable by my neurologist. A few months ago in June, my doctor mentioned I had migraine flarups in June like clockwork every year. I aslo have sever allergies, and to help I started taking benedryl capsules along with Singular and for the first time in years I have not had a “daily “ migraine! If I dont take the benedryl at night, I almost certainly wake up with a pounding migraine. I have also stopped drinking completely since just smelling alocohol triggers a wicked headache.

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  9. Michelle
    17 October 2018 @ 8:56 pm

    I have also noticed that for a time when I took Unisom as a sleep aid (that version used diphenhydramine whch is Benedryl), my migraines abated. I stopped when sleep was no longer a problem. Sometime after when my chronic migraine flared up again and I was put on Topamax, I could not tolerate the side effects. My neurologist was out of ideas. I casually mentioned to him that i thought diphenhydramine might work because of my experience with Unisom and he agreed we should try it. I believe it helped then. I eventually stopped taking it because i found if I didnt have sleep problems, it made me too tired and sleepy the next day.

    Reply

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